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赵振奥


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       赵振奥博士,苏州大学心血管病研究所副教授,2011年博士毕业于东北农业大学,期间从事胚胎着床和胚胎发育的研究。毕业后在中国科学院动物研究所“干细胞与生殖生物学国家重点实验室”从事博士后工作,主要研究内容是小鼠早期胚胎细胞谱系的建立。科研成果发表在PNAS、EMBO J、Open biology、JBC、Fertil Steril等杂志。2015年7月加入心血管病研究所“干细胞与心血管转化医学”研究组,目前工作主要利用发育生物学线索,指导干细胞定向向心血管细胞谱系分化,以及转化应用。


教育与工作经历:

2015 - 至今		苏州大学				副教授
2011 - 2015		中国科学院动物研究所		博士后
2006 - 2011		东北农业大学			博士
2002 - 2006		东北农业大学			学士

科研成果:

[研究论文]

Zhao ZA, Yu Y, Ma HX, Wang XX, Lu X, Zhai Y, Zhang X, Wang H and Li L. The roles of ERAS during cell lineage specification of mouse early embryonic development. Open Biol. 2015; 5:150092.

Lv P, Sheng Y, Zhao ZA, Zhao W, Gu L, Xu T, and Song E. Targeted disruption of Rab10 causes early embryonic lethality. Protein Cell. 2015. 6(6):463-7.

Wei Y, Yang CR, Wei YP, Ge ZJ, Zhao ZA, Zhang B, Hou Y, Schatten H, and Sun QY. Enriched environment-induced maternal weight loss reprograms metabolic gene expression in mouse offspring. J Biol Chem. 2015; 290(8):4604-19.

Xu X, Leng JY, Gao F, Zhao ZA, Deng WB, Liang XH, Zhang YJ, Zhang ZR, Li M, Sha AG, and Yang ZM. Differential expression and anti-oxidant function of glutathione peroxidase 3 in mouse uterus during decidualization. FEBS Lett. 2014; 588(9):1580-9.

Wei Y, Yang CR, Wei YP, Zhao ZA, Hou Y, Schatten H, and Sun QY. Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals. Proc Natl Acad Sci U S A. 2014; 111(5):1873-8.

Liang XH, Deng WB, Li M, Zhao ZA, Wang TS, Feng XH, Cao YJ, Duan EK, and Yang ZM. Egr1 Protein Acts Downstream of Estrogen-Leukemia Inhibitory Factor (LIF)-STAT3 Pathway and Plays a Role during Implantation through Targeting Wnt4. J Biol Chem. 2014; 289(34):23534-45.

Zhang XH, Liang X, Wang TS, Liang XH, Zuo RJ, Deng WB, Zhang ZR, Qin FN, Zhao ZA, and Yang ZM. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) induction on Snail expression during mouse decidualization. Mol Cell Endocrinol. 2013; 381(1-2):272-9.

Xia P, Wang S, Du Y, Zhao ZA, Shi L, Sun L, Huang G, Ye B, Li C, Dai Z, Hou N, Cheng X, Sun Q, Li L, Yang X, and Fan Z. WASH inhibits autophagy through suppression of Beclin 1 ubiquitination. EMBO J. 2013; 32(20):2685-96.

Zhao ZA, Zhang ZR, Xu X, Deng WB, Li M, Leng JY, Liang XH, and Yang ZM. Arachidonic acid regulation of the cytosolic phospholipase A 2alpha/cyclooxygenase-2 pathway in mouse endometrial stromal cells. Fertil Steril. 2012; 97(5):1199-205 e1-9.

Zhang XH, Tian Z, Lei W, Zhao ZA, Wang TS, and Yang ZM. Differential expression of interleukin 1 receptor type II during mouse decidualization. Reprod Sci. 2012; 19(9):923-31.

Su RW, Jia B, Ni H, Lei W, Yue SL, Feng XH, Deng WB, Liu JL, Zhao ZA, Wang TS, and Yang ZM. Junctional adhesion molecule 2 mediates the interaction between hatched blastocyst and luminal epithelium: induction by progesterone and LIF. PLoS One. 2012; 7(4):e34325.

Tian Z#, Zhao ZA#, Liang XH, Zhang XH, Sha AG, Zhang ZR, Yu YS, and Yang ZM. Expression and function of fatty acid-binding protein 4 during mouse decidualization. Fertil Steril. 2011; 95(8):2749-52 e1-5.

Liang XH, Zhao ZA, Deng WB, Tian Z, Lei W, Xu X, Zhang XH, Su RW, and Yang ZM. Estrogen regulates amiloride-binding protein 1 through CCAAT/enhancer-binding protein-beta in mouse uterus during embryo implantation and decidualization. Endocrinology. 2010; 151(10):5007-16.

Hu SJ, Ren G, Liu JL, Zhao ZA, Yu YS, Su RW, Ma XH, Ni H, Lei W, and Yang ZM. MicroRNA expression and regulation in mouse uterus during embryo implantation. J Biol Chem. 2008; 283(34):23473-84.

Chen Y, Ni H, Ma XH, Hu SJ, Luan LM, Ren G, Zhao YC, Li SJ, Diao HL, Xu X, Zhao ZA, and Yang ZM. Global analysis of differential luminal epithelial gene expression at mouse implantation sites. J Mol Endocrinol. 2006; 37(1):147-61.


科研项目:
2015 - 2018		苏州大学人才引进启动项目基金
2013 - 2015		中国博士后科学基金面上资助